产品货号:
Z20362
中文名称:
MC4R抗体
英文名称:
Anti-MC4R Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-MC4R Antibody |
| 指标别名 | melanocortin 4 receptor;BMIQ20;MC4R |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MC4R |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R.The immunogen is located within the first 50 amino acids of MC4R. |
| 计算分子量 | 37kDa |
| 成分 | MC4R Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MC4R Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways.It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity;activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling.MC4R-null mice display maturity onset obesity characterized by hyperphagia,increased adiposity,hyperinsulinaemia and hyperleptinaemia,suggesting that like other obesity-linked genes such as FTO,PTER,and NPC1,MC4R is a potential candidate target for the treatment of obesity. |
| Uniprot ID | P32245 |
| 基因名全称 | Melanocortin 4 receptor |
| 蛋白名全称 | Melanocortin 4 receptor |
| 推荐稀释比 | MC4R antibody can be used for detection of MC4R by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索:MC4R抗体,MC4R多抗,Anti-MC4R Antibody
